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PI, Family, Clan or Protein ID Authors Title Source Year PubMed DOI Category
I04 Gettins,P.G. & Olson,S.T. Use of fluorescence resonance energy transfer to study serpin-proteinase interactions Methods (2004) 32, 110-119. 2004 PubMed DOI Review
I04 Gettins,P.G., Backovic,M. & Peterson,F.C. Use of NMR to study serpin function Methods (2004) 32, 120-129. 2004 PubMed DOI Review
I04 Carrell,R. & Corral,J. What can Drosophila tell us about serpins, thrombosis and dementia? Bioessays (2004) 26, 1-5. 2004 PubMed DOI Suggested therapeutcal potential
I04 Irving,J.A., Pike,R.N., Dai,W., Bromme,D., Worrall,D.M., Silverman,G.A., Coetzer,T.H., Dennison,C., Bottomley,S.P. & Whisstock,J.C. Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases Biochemistry (2002) 41, 4998-5004. 2002 PubMed DOI Design of small-molecule Inhibitors
I04 Plotnick,M.I., Samakur,M., Wang,Z.M., Liu,X.Z., Rubin,H., Schechter,N.M. & Selwood,T. Heterogeneity in serpin-protease complexes as demonstrated by differences in the mechanism of complex breakdown Biochemistry (2002) 41, 334-342. 2002 PubMed DOI
I04 Gettins,P.G. Serpin structure, mechanism, and function Chem Rev (2002) 102, 4751-4804. 2002 PubMed DOI Review
I04 Irving,J.A., Steenbakkers,P.J., Lesk,A.M., Op,d.C., Pike,R.N. & Whisstock,J.C. Serpins in prokaryotes Mol Biol Evol (2002) 19, 1881-1890. 2002 PubMed Review
I04 Pike,R.N., Bottomley,S.P., Irving,J.A., Bird,P.I. & Whisstock,J.C. Serpins: finely balanced conformational traps IUBMB Life (2002) 54, 1-7. 2002 PubMed DOI Review
I04 Gettins,P.G. The F-helix of serpins plays an essential, active role in the proteinase inhibition mechanism FEBS Lett (2002) 523, 2-6. 2002 PubMed DOI Three-dimensional Structure
I04 Peterson,F.C. & Gettins,P.G.W. Insight into the mechanism of serpin-proteinase inhibition from 2D [1H-15N] NMR studies of the 69 kDa alpha1-proteinase inhibitor Pittsburgh-trypsin covalent complex Biochemistry (2001) 40, 6284-6292. 2001 PubMed DOI Three-dimensional Structure
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